Administering aerosol therapy to children can be challenging
Nebulisers, pressurised metered-dose inhalers, soft mist inhalers, and dry powder inhalers are the cornerstone of aerosol therapy in children.2
Device Choice
Appropriate device choice is necessary based on the patient’s age, tolerance and acceptance of the interface (mouthpiece, facemask, hood, etc.) during treatment.2,3
Emotional distress
Emotional distress
On presentation, children may be crying or in respiratory distress, which may negatively impact the dose delivered during inhaled therapy.2,4
Technique
Correct technique by the child or caregiver is required to successfully administer medication.2,3
Improving patient care in response to aerosolised medication1,5
In studies, when compared with jet nebulisers (JN), bronchodilator administration via Aerogen Ultra was associated with:
In children with a moderate-to-severe asthma exacerbation:
- Significantly fewer treatments and significantly less time required to achieve symptom control†1
In patients in an emergency department:
- ~30% relative reduction in hospital admission rates5
- 85% of patients achieved symptom control with one 2.5 mg salbutamol dose5
- 37-minute reduction in emergency department median length of stay5
Aerogen Solo
Single-patient-use device that facilitates aerosol drug delivery at every stage of a patient’s respiratory journey (IMV, NIV, HF and SV).12
- Quick and easy to set up12
- Virtually silent12
- Single patient use12
- 28 days intermittent or 7 days continuous use12
- No added flow12
- Refill medication cup without opening the circuit12
Aerogen Ultra
A handheld device that is used in conjunction with the Aerogen Solo to deliver inhalation treatment either post ventilation or during exacerbations.12,13
- Oxygen port enables optional delivery of oxygen13
- An ergonomic valved mouthpiece controls the flow of air through the chamber to facilitate aerosol drug delivery13
- Innovative chamber design provides an aerosol reservoir intended for optimal drug delivery13
- Extended mouthpiece¶ to easily add bacterial or viral filter13
ED, Emergency Department; HF, high-flow; IMV, invasive mechanical ventilation; JN, jet nebuliser; NIV, non-invasive ventilation; SV, self-ventilating.
†Defined as achieving a mild asthma score following an asthma exacerbation.
‡When placed 15 cm from the Y-Piece in a heated setting; in-vitro model.
§Study performed in healthy subjects.
¶ The Aerogen Ultra with an extended mouthpiece is only available in selected regions. Refer to your in-country instruction manual to determine availability.
- Moody GB, Luckett PM, Shockley CM, et al. Respir Care 2020;65(10):1451–1463.
- Ari A. Ann Transl Med. 2021;9(7):593.
- 2022 GINA Report, Global Strategy for Asthma Management and Prevention. Available at: https://ginasthma.org/gina-reports/ Accessed: January 2023.
- Corcoran TE. Ann Transl Med. 2021;9(7):595.
- Dunne RB, Shortt S. Am J Emerg Med. 2018;36(4):641-646.
- Ari A, Areabi H, Fink JB. Respir Care. 2010;55(7):837-844.
- Ari A, Atalay OT, Harwood R, et al. Respir Care. 2010;55(7):845-851.
- Galindo-Filho VC, Ramos ME, Rattes CS, et al. Respir Care. 2015;60(9):1238-1246.
- Dugernier J, Hesse M, Jumetz T, et al. J Aerosol Med Pulm Drug Deliv. 2017;30(5):349-358.
- Dugernier J, Hesse M, Vanbever R, et al. Pharm Res. 2017;34(2):290-30.
- Berlinski A, Willis JR. Respir Care. 2013;58(7):1124-1133.
- 30-354 Rev U Aerogen Solo Instruction Manual.
- 30-1487 Rev A Aerogen Ultra instruction manual.
GL1442A05-23