Help Centre: FAQs about Aerogen CNTS

Aerogen CNTS

How do I setup the CNTS with an infusion pump?

Insert the syringe filled with medication into the syringe infusion pump and set the appropriate flow rate (refer to the pump manual or manufacturer spec for guidance). To ensure correct and safe connection between the nebuliser and the medication reservoir, trace the medication tube from the nebuliser back to the medication reservoir to make sure the medication tube is connected to the correct source.

What syringe pump software should you use with the CNTS?

The recommended syringe pump software setting with the Aerogen syringe is typically the “BD Plastipak” setting. You must validate this locally before use. Refer to the pump manual or manufacturer spec for guidance. Syringe pumps should be used in accordance with local hospital or ward policies.

What flow rate should I use with the CNTS?

12mL/hour is the Maximum Recommended Input Rate for medication into the Aerogen Solo nebuliser during continuous nebulisation. Use a flow rate of up to 12mL/hour but do not exceed this upper limit.

How does volumetric dosing work with CNTS?

The CNTS drops medication onto the vibrating mesh at a continuous rate. The rate of drug entering the nebuliser determines the drug output rate. This gives you the ability to titrate medication using the infusion rate of the pump. There is no need to change the concentration of the medication in the syringe.

If the infusion rate is low you might see pauses between aerosol being generated; this is a normal finding at low rates and there is no reason for concern.


Example of volumetric dosing: 25mg/hour dose

Question: What infusion rate do I use to deliver 25 mg/hour of albuterol/salbutamol (0.5% solution-5mg/ml)? What is the output of Aerogen Solo for a 25 mg/hour dose of albuterol/salbutamol?


Infusion rate pump =

Aerogen Solo output =

Desired Dosage (mg/hour)
Medication Concentration (mg/ml)


Aerogen Solo output =

25 mg per hour = 5 ml per hour
5 mg /ml


Answer: To deliver 25mg/hour with undiluted 0.5% albuterol/ salbutamol, set the infusion pump rate to 5 ml/hour. The pump rate equals the output of Aerogen Solo.

Why is the fluid level in the aerosol chamber rising?

Rising fluid level in the aerosol chamber indicates that the fill rate has exceeded Aerogen Solo’s nebulisation rate. The recommended input rate of medication into Aerogen Solo during continuous nebulization is up to a maximum of 12mL/hour and should not be exceeded.

How do I fill the Aerogen syringe?

Use another syringe to draw up the medication with a needle or needleless connector. With the plunger pulled back on the Aerogen syringe, insert the medication through the cap end of the Aerogen syringe.

Are pauses in aerosol normal with volumetric dosing?

Yes. Medication is delivered drop-by-drop with volumetric dosing. When solution drops onto the aperture plate, aerosol is produced. There will be a pause in aerosol in between drops. Aerogen Solo’s hourly output will be based on the rate set on the infusion pump.

What is the priming volume of the CNTS tubing?

You should prime the tubing until the medication reaches the end of the tubing. The maximum tubing priming volume is 3.65mL. A rising level of medication in the reservoir may occur if the Aerogen Solo nebuliser is turned off while the feed system is still on, or if the nebuliser is not used in its recommended orientation.