Better is Faster

Trust Aerogen Ultra to deliver a new standard of respiratory patient care.

Compared to a jet nebuliser the Aerogen Ultra delivers significantly more medication in half the time
with improved patient response², helping reduce hospital admissions from the ED³.


High performance aerosol drug delivery

  • Aerogen Ultra delivers significantly more medication in half the time1.
  • Aerogen Ultra delivers a 6-fold increase in medication to the patient’s lungs compared with a standard jet nebuliser3
  • Improves patient response to treatment2
  • Works with and without O25
  • Can be used with a mask or mouthpiece5





Superior Performance across multiple modalities

Aerogen Solo provides superior treatment over the entire care continuum for ventilated and non-ventilated patients.

Aerogen in the Emergency Department

Clinical outcome data demonstrates how Aerogen Ultra is transforming the treatment of patients in the Emergency Department.


WATCH: Dr Dunne talks about Aerogen Ultra’s success in the ED

Study Design
A retrospective chart review of 1,594 patients at St. John Hospital and Medical Center, Detroit (USA) compared clinical outcomes associated with the use of a hospital standard jet nebuliser versus the Aerogen Ultra.
37min

median reduction in ED length of stay

32%

reduction in admission rates

85%

of patients achieving symptom control with one 2.5mg salbutamol dose


30%

higher discharge rates


Download Paper

Patient Results: Bronchodilator Response

Spontaneous breathing / Lung Function

Aerogen Ultra demonstrated a significant improvement in FVC in response to a single standard bronchodilator dose when compared to a Jet Nebuliser (JN)1 Aerogen Ultra was associated with clinically significant improvements in inspiratory capacity (10% of predicted), FVC (>12% and >200ml) and a reduction in residual volume (>300ml)1

Borg Symptom score

Trend to significant when comparing the two nebulisers (p=0.08) Since exacerbation recovery is associated with improved lung volume2, enhanced bronchodilator delivery with Aerogen Ultra may therefore accelerate exacerbation recovery.

Cushen et al. Poster presentation at BTS 2016
Cushion et al. Respiratory medicine, 2016, 119:55-62

Aerogen Ultra delivers 6X greater lung dose*

Aerogen Ultra

Jet Nebuliser

Lung dose delivered: Aerogen Ultra 34.1%; Jet Nebuliser 5.2% (p < 0.001) Residual dose volume: Aerogen Ultra 2.4%; Jet Nebuliser 62.8% (p = 0.008)

Nebulisers were filled with diethylenetriaminepentaacetic acid labelled with
technetium-99 m (99mTc-DTPA, 2 mCi/4 mL) Dugernier J. et al 20174

*Aerogen Ultra compared to a standard Jet Nebuliser.

Download the paper

Aerogen Ultra delivers significantly more medication in half the time

Hickin et al. Poster at the College of Emergency Medicine Clinical Excellence Conference 2014

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References

1. Hickin S, Mac Loughlin R, Sweeney L, Tatham A and Gidwani S. Comparison of mesh nebuliser versus jet nebuliser in simulated adults with chronic obstructive pulmonary disease. Poster at the College of Emergency Medicine Clinical Excellence Conference. 2014. 2. Cushen B, et al. BTS poster presentation. 2016 3. Dunne RB and Shortt S. Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department. The American journal of emergency medicine. 2017. 4. Dugernier et al. SPECTCT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. Pharm Res. 2016 Nov 7 (epub). 5. Aerogen Solo Instruction Manual.