Compared to a jet nebuliser the Aerogen Ultra delivers significantly more medication in half the time
with improved patient response², helping reduce hospital admissions from the ED³.
Aerogen Solo provides superior treatment over the entire care continuum for ventilated and non-ventilated patients.
Aerogen Ultra demonstrated a significant improvement in FVC in response to a single standard bronchodilator dose when compared to a Jet Nebuliser (JN)1 Aerogen Ultra was associated with clinically significant improvements in inspiratory capacity (10% of predicted), FVC (>12% and >200ml) and a reduction in residual volume (>300ml)1
Trend to significant when comparing the two nebulisers (p=0.08) Since exacerbation recovery is associated with improved lung volume2, enhanced bronchodilator delivery with Aerogen Ultra may therefore accelerate exacerbation recovery.
Cushen et al. Poster presentation at BTS 2016
Cushion et al. Respiratory medicine, 2016, 119:55-62
Lung dose delivered: Aerogen Ultra 34.1%; Jet Nebuliser 5.2% (p < 0.001) Residual dose volume: Aerogen Ultra 2.4%; Jet Nebuliser 62.8% (p = 0.008)
Nebulisers were filled with diethylenetriaminepentaacetic acid labelled with
technetium-99 m (99mTc-DTPA, 2 mCi/4 mL) Dugernier J. et al 20174
*Aerogen Ultra compared to a standard Jet Nebuliser.
Hickin et al. Poster at the College of Emergency Medicine Clinical Excellence Conference 2014
1. Hickin S, Mac Loughlin R, Sweeney L, Tatham A and Gidwani S. Comparison of mesh nebuliser versus jet nebuliser in simulated adults with chronic obstructive pulmonary disease. Poster at the College of Emergency Medicine Clinical Excellence Conference. 2014. 2. Cushen B, et al. BTS poster presentation. 2016 3. Dunne RB and Shortt S. Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department. The American journal of emergency medicine. 2017. 4. Dugernier et al. SPECTCT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. Pharm Res. 2016 Nov 7 (epub). 5. Aerogen Solo Instruction Manual.