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Recommended Articles

2016
A Pilot Study To Assess Bronchodilator Response During An Acute Exacerbation Of COPD Using A Vibrating Mesh Nebuliser Versus Jet Nebuliser For Bronchodilator Delivery
B Cushen, A Alsaid, A Abdulkareem, RW Costello
2017
Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department
Robert B. Dunne, Sandra Shortt
2016
Aerogen Clinical White Paper

Publication Search Results (65)

Aerosol Delivery in a Pediatric Model of Non-Invasive Ventilation
Velasco JM and Berlinski A
Respiratory Care Epub
2017
Summary
  • Aerogen Solo provided highest delivery regardless of position or inspiratory pressure
  • Solo connected to the mask or close to the Y in the inspiratory limb provided better delivery than at the humidifier in this pediatric dual-limb NIV circuit
Comparison of bronchodilator administration with vibrating mesh nebulizer and standard jet nebulizer in the emergency department
Robert B. Dunne, Sandra Shortt
The American Journal of Emergency Medicine
2017
Summary
Retrospective study showing significantly improved outcomes for all patients requiring albuterol in the ED when delivery was via Aerogen Ultra compared to standard jet nebulizers:
  • 32% reduction in admissions
  • 30% higher discharges from the ED
  • 37 minute reduction in median length of stay
  • 75% reduction in albuterol dose
Comparison of response to aerosol drug delivery with mesh and jet nebulizers during non-invasive ventilation (NIV) in acute exacerbation of COPD
Sergey AVDEEV, Galia NURALIEVA, Aung Kyaw SOE, James B. FINK
Poster presentation at ERS 2017
2017
Summary
Bronchodilators administered with Aerogen Solo during NIV during acute exacerbation COPD resulted in improved pulmonary function and BORG symptom score
Methacholine Challenge: Comparison of Airway Responsiveness Produced by a Vibrating Mesh Nebulizer Versus a Jet Nebulizer
Blais CM, Cockcroft DW, Veilleux J, Boulay MÈ, Boulet LP, Gauvreau GM, Scime TX, Watson RM, O'Byrne PM, Davis BE.
J Aerosol Med Pulm Drug Deliv. 2017 [Epub ahead of print]
2017
Summary
  • Lack of evaporation with vibrating mesh (Aerogen Solo) allows for more accurate determination of dose
  • Lack of availability combined with evaporation loss from jet nebulizers (75-85%) render jet nebulizers less than ideal for accurate assessment of dose of methacholine delivered
  • Use of the Aerogen Solo could address many difficulties associated with MCT (i.e. disposable, no need for driving gas, remove potential error when setting flow, etc.)
Methacholine Challenge Testing: A Novel Method for Measuring PD20
Davis BE, Simonson SK, Blais CM, Cockcroft DW.
Chest. 2017 Dec;152(6):1251-1257.
2017
Summary
  • Aerogen Solo provides a simple, repeatable method for MCT that meets new ATS guidelines
  • The new method (volumetric dosing) with Aerogen Solo produces similar PD20 data with a well-characterized JN and standardized tidal breathing methodology.
Aerogen: Pioneering Aerosol Drug Delivery
Amy Tatham
2016
Summary
The Aerogen nebulizers provide superior aerosol therapy within the intensive care environment during ventilation, NIV, NHF and is now available for use with spontaneously breathing patients.
A Case Study: Use of Vibrating Mesh with a Valved Adapter in a Pediatric Patient with a Severe Asthma Exacerbation
Thayer T, Hodgens E and Lieberman S
Respiratory Therapy Case Study
2016
Summary
Changing from an open mask to the mouthpiece with the Aerogen Ultra resulted in a rapid clinical response.
Particle Size Characterization of Nebulized Albuterol Delivered by a Vibrating Mesh Nebulizer Through Pediatric Endotracheal Tubes
Ariel Berlinski and Sathyanand Kumaran
Poster Presentation at ATS 2016
2016
Summary
During infant ventilation with bias flow, more than 2 fold more drug is delivered when placed at the wye compared to the humidifier
Comparison of Aerosol Deposition with Heated and Unheated High Flow Nasal Cannula (HFNC) in Healthy Adults
Alcoforado L, Ari A, De Melo Barcelar J, Brandao SS, Fink JB and Dornelas De Andrade A.
Poster presentation at ATS
2016
Summary
A lung dose of 10.6% is achievable at a flow rate of 10L/min. Lower flow rates correlate with higher drug deposition.
SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study
Dugernier J, Hesse M, Vanbever R, Depoortere V, Roeseler J, Michotte JB, Laterre PF, Jamar F, Reychler G
Pharm Res. 2017 Feb;34(2):290-300
2016
Summary
Lung dose was six times higher with the Ultra (34.1%) vs Jet Neb (5.2%)
Comparison of Aerosol Delivery During Simulated Adult Noninvasive Positive Pressure Ventilation: Nebulizer versus Pressurized Metered-dose Inhaler
Hua Wang, Michael T McCormack, C Scott Elder, Daniel Church, J Francis Turner, Rajiv Dhand.
Poster presentation at ATS
2016
Summary
  • During single limb NIV higher drug delivery was observed when Aerogen was placed on the patient side of the leak port compared to a SVN and MDI
  • Very poor drug delivery was observed with an MDI
Nasal High Flow Nebulization in Infants and Toddlers: An In Vitro and In Vivo Scintigraphic Study
Reminiac F, Vecellio L, Mac Loughlin RM, Le Pennec D, Cabrera M, Vourc'h NH, Fink JB and Ehrmann S
Pediatr Pulmonol. 2017 Mar;52(3):337-344
2016
Summary
Using Aerogen provides similar aerosol deposition as standard treatment with the added benefit of providing high flow therapy at the same time
Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study
Dugernier J, Reychler G, Wittebole X, Roeseler J, Depoortere V, Sottiaux T, Michotte JB, Vanbever R, Dugernier T, Goffette P, Docquier MA, Raftopoulos C, Hantson P, Jamar F and Laterre PF
Annals of Intensive Care. 2016;6:73.
2016
Summary
-Actual lung deposition of 10-15% when AErogen Solo is placed at the wye with bias flow during ventilation -Higher aerosol deposition with volume vs pressure controlled ventilation
Aerosol Delivery Using Jet Nebulizer and Vibrating Mesh Nebulizer During High Frequency Oscillatory Ventilation: An In Vitro Comparison
Fang TP, Lin HL, Chiu SH, Wang SH, DiBlasi RM, Tsai YH and Fink JB
J Aerosol Med Pulm Drug Deliv 2016 Oct;29(5):447-453.
2016
Summary
Aerogen Solo outperforms SVNs when positioned proximal to the patient in adult, pediatric and infant models
Financial effect of converting ipratropium-albuterol therapy from inhalers to nebulizer treatments at an academic health system
Loborec SM, Johnson SE and Keating EA.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2016;73:121-5.
2016
Summary
Change to Aerogen Solo  from MDIs resulted in a 3-month savings of $99,359 in drug cost and an extrapolated full-year savings of $397,436.
Effect of Aerosol Devices and Administration Techniques on Drug Delivery in a Simulated Spontaneously Breathing Pediatric Tracheostomy Model
Alhamad BR, Fink JB, Harwood RJ, Sheard MM and Ari A
Respiratory care. 2015;60:1026-32
2016
Summary
The Aerogen Solo  delivered a greater inhaled mass than a pMDI or SVN during pediatric ventilation through a tracheostomy
Aerosol Therapy in Adults Receiving High Flow Nasal Cannula Oxygen Therapy
Reminiac F, Vecellio L, Heuze-Vourc'h N, Petitcollin A, Respaud R, Cabrera M, Pennec DL, Diot P and Ehrmann S
Journal of aerosol medicine and pulmonary drug delivery. 2016;29:134-41
2016
Summary
Aerogen deposited significantly more drug in the lungs at the lower flow rate of 30 l/min vs 45 l/min and 60 l/min
High-Flow Nasal Cannula and Aerosolized beta Agonists for Rescue Therapy in Children With Bronchiolitis: A Case Series
Morgan SE, Mosakowski S, Solano P, Hall JB and Tung A
Respiratory care. 2015;60:e161-5
2016
Summary
Aerogen Solo nebulization during Nasal High Flow was better tolerated than a standard jet nebulizer with aerosol mask.
Aerogen Clinical White Paper
2016
Summary
A Pilot Study To Assess Bronchodilator Response During An Acute Exacerbation Of COPD Using A Vibrating Mesh Nebuliser Versus Jet Nebuliser For Bronchodilator Delivery
B Cushen, A Alsaid, A Abdulkareem, RW Costello
Poster Presentation at BTS
2016
Summary
Significant improvement in lung function (FVC) with an accompanied improvement in patient’s breathlessness score during COPD exacerbation with just a single 2.5mg salbutamol dose delivered with the Aerogen Ultra.
Comparison Of Aerosol Delivery With Three High Flow Nasal Cannula Types And Sizes
Darlene Pacocha, Tina Thayer, Patricia A Dailey, Greg Gagnon
AARC Poster
2016
Summary
  • All systems showed equivalent or better aerosol delivery during HFNC with Aerogen
  • At 50 L/min inhaled dose was greater with large cannnula compared to small and medium for Fisher & Paykel and Flexicare
Effect of Nebulizer Type and Position on Aerosol Drug Delivery during Support Mechanical Ventilation and Spontaneously Breathing for Tracheostomized Adult Patients.
Patrick M. Kelly, Andrew O’Sullivan, Cathy McKenna, Louise Sweeney & Ronan MacLoughlin.
Poster presentation at DDL 2016
2016
Summary
The Aerogen Solo delivered a significantly great amount of aerosol (P-values <0.05) when compared to a jet nebuliser  for all positions evaluated (dry side of the humidifier and at tracheostomy tube) during spontaneously breathing and mechanical ventilation in tracheostomy patients.
Assessment of Exhaled Aerosol Emissions using two Prevalent Nebuliser Technologies in Clinical Use Today
Andrew O’Sullivan, James McGrath, Miriam Byrne, Patrick Power and Ronan Mac Loughlin
Poster presentation at DDL 2016
2016
Summary
Aerosol emissions are greatly reduced with the use of a mouthpiece and valved facemask when used with the Aerogen Ultra
Physicochemical aspects and efficiency of albuterol nebulization: comparison of three aerosol types in an in vitro pediatric model
Sidler-Moix AL, Di Paolo ER, Dolci U, Berger-Gryllaki M, Cotting J and Pannatier A.
Respiratory care. 2015;60:38-46.
2015
Summary
Aerogen aerosol devices deliver more aerosols than SVNs and ultrasonic nebulizers.   .
Performance Improvement Plan for Pediatric Patients in Respiratory Distress: Clinical Experience
Patricia Dailey, BS, RRT, Thayer Tina, RRT, John Santos, RRT, Puncho Gurung, MD
Respiratory Therapy Volume 10 Number 1 Winter 2015
2015
Summary
A performance improvement plan including the use of noninvasive methods of ventilatory support and efficient advanced aerosol techniques using the Aerogen Solo had a positive impact on clinical outcomes, as well as staff and patient satisfaction
Radioaerosol Pulmonary Deposition Using Mesh and Jet Nebulizers During Noninvasive Ventilation in Healthy Subjects
Galindo-Filho VC, Ramos ME, Rattes CS, Barbosa AK, Brandao DC, Brandao SC, Fink JB and de Andrade AD
Respiratory care. 2015;60:1238-46
2015
Summary
Aerosol therapy using the NIVO nebulizer resulted in 3 fold higher pulmonary deposition than a JET nebulizer during non-invasive ventilation  
Analysis of Deposition Radioaerosol Nebulizers Membrane in Healthy Subjects
Luciana Alcoforado, Jaqueline de Melo Barcelar, Valdecir Castor Galindo, Simone Cristiana S. Brandao, James B Fink, Armele Dornelas de Andrade.
Presented at ISAM 2015
2015
Summary
4 fold more lung dose was achieved with the Ultra compared to a jet neb
Performance Comparisons of Jet and Mesh Nebulizers Using Different Interfaces in Simulated Spontaneously Breathing Adults and Children
Ari A, Dornelas de Andrade A, Sheard M, AlHamad B, Fink JB
Journal of Aerosol Medicine and Pulmonary Drug Delivery 28(4) 281-9
2015
Summary
In spontaneous breathers the Aeroneb Solo Adapter achieves 4.5 fold higher inhaled dose than a standard small volume nebulizer
Pediatric Patient with Severe Asthma Treated with a Vibrating Mesh with Valved Adapter
Newsome T, Thayer T and Lieberman S
Respiratory Therapy Case Study
2015
Summary
Changing from an open to a valved mask with Aerogen Ultra improved lung dose, reduced aerosol loss, improved patient clinical response and improved patient satisfaction.
Inhaled beta2-Agonist Therapy Increases Functional Residual Capacity in Mechanically Ventilated Children With Respiratory Failure
Ramsi MA, Henry M, Milla CE and Cornfield DN
Pediatric critical care medicine. 2015;16:e189-93
2015
Summary
Improved  Functional residual capacity (FRC) by 18.3% after bronchodilator treatment using Aerogen Solo.
Comparison of HFNC, bubble CPAP and SiPAP on aerosol delivery in neonates: An in-vitro study
Sunbul FS, Fink JB, Harwood R, Sheard MM, Zimmerman RD and Ari A
Pediatric pulmonology. 2015;50:1099-106
2015
Summary
Aerogen achieved optimal drug delivery via HFNC, SiPAP and bubble CPAP when positioned dry side of the humidifier
In Vitro Evaluation of Radiolabeled Aerosol Delivery via a Variable Flow Infant CPAP System
Farney KD, Kuehne BT, Gibson LA, Nelin LD, Shepherd EG
Respiratory Care 59(3) 340-4
2014
Summary
Effective aerosol delivery can be achieved during infant variable flow NCPAP
Quantifying aerosol delivery in spontaneously breathing patients with tracheostomy using different humidification systems with or without exhaled humidity
Arzu Ari, Bshayer Alhamad, Robert Harwood, Meryl Sheard, James B Fink
Presentation Abstract at the American College of Chest Physicians
2014
Summary
The Aeroneb Solo outperformed the small volume nebulizer with all humidification systems in a simulated tracheostomy patient
Comparison of mesh nebuliser versus jet nebuliser in simulated adults with chronic obstructive pulmonary disease
Hickin, S., MacLoughlin, R., Sweeney, L., Tatham, A., and Gidwani, S
Poster at the College of Emergency Medicine Clinical Excellence Conference.
2014
Summary
The Aerogen Ultra is faster and more effective than a jet nebuliser, delivering more salbutamol over a shorter period of time.
Identification and validation of nebulized aerosol devices for sputum induction.
Davidson WJ, Dennis J, The S, Litoski B, Pieron C, Leigh R.
Canadian Respiratory Journal. 2014 Mar-Apr;21(2):101-6. Epub 2013 Nov 28.
2014
Summary
"We have formally adopted the Aeroneb Solo device as the nebuliser of choice in our clinical sputum induction program at the University of Calgary"
Bronchodilator delivery during simulated non-invasive ventilation of a pediatric asthmatic
Cynthia C. White, Dave N Crotwell, Shuijie Shen, Delphine Yung, John Salyer, and Robert M. DiBlasi
Respir Care. 2013 Sep;58(9):1459-66
2013
Summary
Increased albuterol was delivered in a lung model with the NIVO nebulizer which is placed in the mask and therefore after the exhalation valve
Albuterol Delivery by 4 Different Nebulizers Placed in 4 Different Positions in a Pediatric Ventilator In-Vitro Model
Berlinski A, Willis JR.
Respir Care. 2013 Jul;58(7):1124-33.
2013
Summary
The Aeroneb Solo performance was superior to small volume nebulizers regardless of the position in the ventilator circuit
Evaluation of vibrating mesh nebulizer performance during Nasal High Flow therapy
R Mac Loughlin, P Power, M Wolny, C Duffy
Abstracts: International Society for Aerosols in Medicine 19th International Congress Journal of Aerosol Medicine and Pulmonary Drug Delivery Volume 26, Number 2, 2013 DOI: 10.1089/jamp.2013.00A1
2013
Summary
Lung dose during Nasal High Flow is comparable to those reported in the literature with vibrating mesh nebulizers during both invasive and non-invasive mechanical ventilation.
Conversion from metered dose inhalers to a vibrating mesh nebulizer in long term acute care hospitals: cost effectiveness and respiratory staff perception
Streepy, K. S., Dawson, A.M., Grigonis, A.M., Hammerman, S.I., Snyder, L.K.
Poster presentation at American Society of Health-System Pharmacists
2013
Summary
Substantial cost savings have been acknowledged after transition from MDIs to the Aerogen Solo used during ventilation in 13 long term acute care hospitals
Impact on quality and cost savings with transition of ipratropium/albuterol inhaler to nebulizer in ventilated patients
Gary Blake, Joseph Yaklic, Janet Cobb
Poster presentation at American Society of Health-System Pharmacists
2013
Summary
Cost per patient was reduced to $46 from $191 after transition from MDI to the Aeroneb Solo during ventilation. Potential (105 hospitals) implementation could lead to annual savings from $870,000 - $1,740,000
Conversion of Pressurized Metered-Dose Inhaler to Vibrating Mesh Nebulizer Administered Medications
Cara McDaniel, Brian Glynn, Steven Gudowski, Tiffany Pezzano, Sandra Weibel
Poster presentation at the Society of Critical Care Medicine
2013
Summary
Conversion from MDI to Aeroneb Solo resulted in significant cost savings and no change in clinical outcomes or staff satisfaction
Evaluation of vibrating mesh nebulizer, jet nebulizer and pMDI performance during simulated adult and paediatric CPAP and NIPPV
P Power, R MacLoughlin, M Wolny, C Duffy
Abstracts: International Society for Aerosols in Medicine 19th International Congress Journal of Aerosol Medicine and Pulmonary Drug Delivery Volume 26, Number 2, 2013 DOI: 10.1089/jamp.2013.00A1
2013
Summary
The NIVO achieved the highest Respirable Dose of the three aerosol generators tested across both adult and paediatric CPAP and NIPPV settings
Aerosol therapy during mechanical ventilation: an international survey
Ehrmann S, Roche-Campo F, Sferrazza Papa GF, Isabey D, Brochard L, Apiou-Sbirlea G; REVA research network.
Intensive Care Med. 2013 Jun;39(6):1048-56
2013
Summary
Aerosol therapy during mechanical ventilation is used by more than 95 % of intensivists mainly to deliver bronchodilators and steroids. A breakdown of the drugs and nebulisers used worldwide is presented.
Severe intraoperative bronchospasm treated with a vibrating-mesh nebulizer
Leonard R. Golden, Helen Ann DeSimone, Farhad Yeroshalmi, Mindaugas Pranevicius and Mana Saraghi
Anesthesia progress. 2012;59:123-126
2012
Summary
The Aeroneb Pro was used to relieve bronchospasm in an intubated 3-year-old girl after MDI and jet nebulizers were unsuccessful.
Comparisons of the RAM Cannula with High Flow Nasal Cannula (HFNC) on aerosol drug delivery in a simulated neonatal lung model
Arzu Ari, Robert Harwood, Hui-Lin Ling, Robert DiBlasi, William Callas, Meryl Sheard, Debbie Gilley, Tracey Roberts, Vickie Arnolde, James Fink
AARC poster 2012
2012
Summary
Aerosol delivery during Nasal High Flow is more efficient than the RAM cannula in a simulated neonatal lung model
Comparison of aerosol delivery using the Aerogen micropump and jet nebulizer in a closed-system ventilator circuit
Kimberly Farney, Brandon Kuehne, Jennah Hollen, Laurie Gibson
AARC poster 2012
2012
Summary
The Aeroneb Solo delivered four fold more aerosolized medication than a jet nebulizer during simulated mechanical ventilation
In vitro comparison of emitted dose with 2 types of nebulizers during non invasive ventilation
J.B. Michotte, E. Jossen, J. Roeseler, G. Liistro, G. Reychler
ERS conference poster 2012
2012
Summary
The Aeroneb Pro and Aeroneb Solo have a greater emitted/inhaled dose compared to a Jet Nebulizer in a simulated adult model of non-invasive ventilation. Dose increased with both nebulizers positioned on the patient side of the exhalation/leak port
Improved Aerosol Drug Delivery With An Electronic Mesh Nebulizer During Non—Invasive Ventilation
Michael McPeck
AARC poster 2012
2012
Summary
In vitro model of CPAP and non-invasive ventilation demonstrated increased inhaled mass with the NIVO compared to a small volume nebulizer. The NIVO treatment time was also reduced and minimal residual volume was observed
In vitro comparison of heliox and oxygen in aerosol delivery using pediatric high flow nasal cannula
Arzu Ari, Robert Harwood, Meryl Sheard, Patricia Dailey and James B. Fink
Pediatr Pulmonol. 2011 Aug;46(8):795-801. doi: 10.1002
2011
Summary
Efficient delivery of aerosol is observed during Nasal High Flow, where aerosol delivery is higher at lower flows. Heliox improves aerosol deposition at higher flows.
Cost reduction using Aeroneb Solo in a medical ICU ventilator population
John S. Emberger, Joel M. Brown II, Lori Killian
AARC Poster 2011
2011
Summary
Clinical outcomes were similar after a change in practice from MDI to the Aeroneb Solo. There was a $57,854.24 cost reduction after implementation of Aeroneb Solo
Efficiency of aerosol devices during non-invasive ventilation in simulated adult lung model
Maher M. AlQuaimi, James Fink, Robert Harwood, Arzu Ari
AARC poster 2011
2011
Summary
Jet nebulizers are less efficient than the Aeroneb Solo or pMDI in a simulated model of non-invasive ventilation. The Aeroneb Solo had a significantly lower residual volume than the jet nebulizer
The relative lung and systemic bioavailability of terbutaline following nebulisation in non-invasively ventilated patients
Abdelrahim ME, Plant PK, Chrystyn H.
Int J Pharm 2011 Nov 28;420(2):313-8
2011
Summary
A urinary pharmacokinetic method of drug excretion was used to show the performance of the Aeroneb Pro and a jet nebuliser during non-invasive ventilation with COPD patients. The Aeroneb Pro was deemed the more efficient nebuliser.
In-vitro characterisation of the nebulised dose during non-invasive ventilation
Mohamed E. Abdelrahim, Paul Plant and Henry Chrystyn
J Pharm Pharmacol. 2010 Aug;62(8):966-72
2010
Summary
Inhaled dose was greater for the Aeroneb Pro than the jet nebulizer when positioned both patient side and ventilator side of the leak port. The respirable dose is significantly higher when the nebulizer is positioned patient side of the leak port
Evaluation of aerosol generator devices at 3 locations in humidified and non-humidified circuits during adult mechanical ventilation
Arzu Ari, Hasan Areabi and James B Fink
Respir Care. 2010 Jul;55(7):837-44.
2010
Summary
The mean inhaled dose delivered by the Aeroneb Solo was 3-fold greater than a jet nebulizer with a heated and humidified mechanical ventilation circuit
Influence of nebulizer type, position, and bias flow on aerosol drug delivery in simulated pediatric and adult lung models during mechanical ventilation
Arzu Ari, Orcin Telli Atalay, Robert Harwood, Meryl M Sheard, Essam A Aljamhan and James B Fink
Respir Care. 2010 Jul;55(7):845-51.
2010
Summary
The mean inhaled dose delivered by the Aeroneb Solo was 2–3-fold greater than the jet nebulizer during simulated mechanical ventilation
Clearing the mist from our eyes: bronchodilators, mechanical ventilation, new devices, locations, and what you should know about bias flow
Rob DiBlasi
Respir Care. 2010 Jul;55(7):942-6.
2010
Summary
Editorial discussing Arzu Ari publications on aerosol therapy during mechanical ventilation
In vitro study of salbutamol aerosol delivered during neonatal mechanical ventilation
L. Vecellio, E. Mercier, J. Fink, C. Duffy and P. Diot
Journal of Aerosol Medicine and Pulmonary Drug Delivery. June 2009, 22(2): 173. doi:10.1089/jamp.2008.00A3.
2009
Summary
The Aeroneb Solo nebulizer is more efficient than the Mistyneb Jet Nebulizer during neonatal simulated mechanical ventilation
Aerosol delivery through adult High Flow Nasal Cannula: An in vitro comparison with heliox and oxygen
Patricia A. Dailey, Kyle Walsh, James B. Fink, Robert Harwood, Arzu Ari
AARC poster 2009
2009
Summary
An in vitro model of aerosol delivery with the Aeroneb Solo and Nasal High Flow demonstrated increased aerosol delivery with heliox and with decreasing flow
In vitro performances of Aeroneb Solo with salbutamol during adult mechanical ventilation
L. Vecellio, E. Mercier, J. Fink, C. Duffy and P. Diot
Journal of Aerosol Medicine and Pulmonary Drug Delivery. June 2009, 22(2): 173. doi:10.1089/jamp.2008.00A3.
2009
Summary
The Aeroneb Solo nebulizer is more efficient than the Mistyneb Jet Nebulizer during adult simulated mechanical ventilation
Case Report: Status Asthmaticus Refractory to Conventional Treatment
Patricia Dailey
Neonatal Intensive Care
2008
Summary
Case study of a ventilated pediatric patient with severe asthma treated with albuterol using the Aeroneb Solo
Aerosol delivery through nasal cannulas: an in vitro study
Abhiram R. Bhashyam, Matthew T. Wolf And Amy L. Marcinkowski, Al Saville, Kristina Thomas, Joseph A. Carcillo and Timothy E. Corcoran
J Aerosol Med Pulm Drug Deliv. 2008 Jun;21(2):181-8.
2008
Summary
In vitro aerosol therapy can be effectively delivered non-invasively with Nasal High Flow and the Aeroneb Solo
Aerosol deposition in neonatal ventilation
Dubus JC, Vecellio L, De Monte M, Fink JB, Grimbert D, Montharu J, Valat C, Behan N, Diot P
Pediatr Res. 2005 Jul;58(1):10-4.
2005
Summary
~25-fold greater lung deposition with the Aeroneb Pro compared to a Jet nebulizer (MistyNeb) in an neonatal animal model of mechanical ventilation
Aerosol delivery to ventilated infant and pediatric patients
Jim Fink
Respir Care. 2004 Jun;49(6):653-65
2004
Summary
Review of aerosol delivery to ventilated infant and pediatric patients
Aerosol delivery during mechanical ventilation with high frequency oscillation: an in vitro evaluation
James B. Fink
American College of Chest Physicians Annual Meeting (ACCP), November 2001
2001
Summary
The Aeroneb Pro delivered more albuterol during high frequency oscillation compared with 2 jet nebulizers
Case Study: Administration of heliox and bronchodilator aerosol via high flow nasal cannula in a severe asthmatic
Patricia Dailey
Summary
Case study of the use of the Aeroneb Solo during Nasal High Flow to deliver albuterol to a severe asthmatic patient